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Cell line expression and mutations
Josip edited this page Apr 30, 2021
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Processing expressions from Cosmic:
- CSV files containing expressions for cell lines should be saved in
./genes/expressions/
under name <cell_line_name>.csv. They should be manually downloaded from Cosmic database-a. - files with filtered z-scores for every cell line are saved in
./genes/expressions/
under nameexpression_score_<cell_line>.csv
python calculate_gene_expression_cell_line.py -g ./genes/uniprot_entries_null.txt -c MDA-MB-231
Getting mutations from Cosmic and processing them:
python get_gene_mutation_cell_line.py -g ./genes/uniprot_entries_null.txt -c MDA-MB-231
python generateMutatedFASTAseqCellLine.py -g ./genes/uniprot_entries_null.txt