diff --git a/anndata/_core/merge.py b/anndata/_core/merge.py
index 9f53ea3a6..6e7f94172 100644
--- a/anndata/_core/merge.py
+++ b/anndata/_core/merge.py
@@ -29,7 +29,7 @@
 from scipy.sparse import spmatrix
 
 from .anndata import AnnData
-from ..compat import AwkArray, DaskArray, CupySparseMatrix, CupyArray
+from ..compat import AwkArray, DaskArray, CupySparseMatrix, CupyArray, CupyCSRMatrix
 from ..utils import asarray, dim_len
 from .index import _subset, make_slice
 from anndata._warnings import ExperimentalFeatureWarning
@@ -153,6 +153,10 @@ def equal_sparse(a, b) -> bool:
     xp = array_api_compat.array_namespace(a.data)
 
     if isinstance(b, (CupySparseMatrix, sparse.spmatrix)):
+        if isinstance(a, CupySparseMatrix):
+            # Comparison broken for CSC matrices
+            # https://github.com/cupy/cupy/issues/7757
+            a, b = CupyCSRMatrix(a), CupyCSRMatrix(b)
         comp = a != b
         if isinstance(comp, bool):
             return not comp
diff --git a/anndata/tests/test_views.py b/anndata/tests/test_views.py
index 06570e672..29fc10e09 100644
--- a/anndata/tests/test_views.py
+++ b/anndata/tests/test_views.py
@@ -327,8 +327,14 @@ def test_set_scalar_subset_X(matrix_type, subset_func):
 
     assert adata_subset.is_view
     assert np.all(asarray(adata[subset_idx, :].X) == 1)
-
-    assert asarray((orig_X_val != adata.X)).sum() == mul(*adata_subset.shape)
+    if isinstance(adata.X, CupyCSCMatrix):
+        # Comparison broken for CSC matrices
+        # https://github.com/cupy/cupy/issues/7757
+        assert asarray((orig_X_val.tocsr() != adata.X.tocsr())).sum() == mul(
+            *adata_subset.shape
+        )
+    else:
+        assert asarray((orig_X_val != adata.X)).sum() == mul(*adata_subset.shape)
 
 
 # TODO: Use different kind of subsetting for adata and view