diff --git a/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/runtime/ReactHostImpl.java b/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/runtime/ReactHostImpl.java
index a5732d3c893c13..b9fc10da9d0705 100644
--- a/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/runtime/ReactHostImpl.java
+++ b/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/runtime/ReactHostImpl.java
@@ -923,6 +923,17 @@ private Task<Void> getOrCreateStartTask() {
     final String method = "getOrCreateStartTask()";
     if (mStartTask == null) {
       log(method, "Schedule");
+      Assertions.assertCondition(
+          ReactNativeFeatureFlags.enableBridgelessArchitecture(),
+          "enableBridgelessArchitecture FeatureFlag must be set to start ReactNative.");
+
+      Assertions.assertCondition(
+          ReactNativeFeatureFlags.enableFabricRenderer(),
+          "enableFabricRenderer FeatureFlag must be set to start ReactNative.");
+
+      Assertions.assertCondition(
+          ReactNativeFeatureFlags.useTurboModules(),
+          "useTurboModules FeatureFlag must be set to start ReactNative.");
       mStartTask =
           waitThenCallGetOrCreateReactInstanceTask()
               .continueWithTask(